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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12622921 B1

PDFFull Text
Date of Patent:
May. 12, 2026

Filed:

Aug. 29, 2022

Stable formulations comprising thiotepa

Applicant:

Shorla Pharma Ltd., County Tipperary, IE;

Inventors:

Sharon Cunningham, County Tipperary, IE;

Orlaith Ryan, County Tipperary, IE;

Johannes Jan Platteeuw, Boxtel, NL;

Assignee:

SHORLA PHARMA LTD., County Tipperary, IE;

Attorney:

Harness, Dickey & Pierce, P.L.C.

Primary Examiner:

Layla Soroush

Int. Cl.
CPC ...
A01N 43/00 (2006.01); A01N 43/46 (2006.01); A61K 9/08 (2006.01); A61K 31/55 (2006.01); A61K 31/675 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/18 (2017.01); A61K 47/20 (2006.01); A61K 47/22 (2006.01);
U.S. Cl.
CPC ...
A61K 31/675 (2013.01); A61K 9/08 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/18 (2013.01); A61K 47/20 (2013.01); A61K 47/22 (2013.01);
Abstract

The present disclosure provides pharmaceutical compositions comprising thiotepa and one selected from PEG, such as PEG400 or PEG600, and DMSO, and optionally water or an aqueous saline solution and thiosulfate. The composition is free or substantially free of impurities. Also provided is a method for treating cancer in a subject, or myeloablation prior to bone marrow transplantation using the composition. A method for enhancing the stability of a thiotepa formulation is also contemplated.

Find Patent Forward Citations

Cunningham, Sharon. (2026). Stable formulations comprising thiotepa (U.S. Patent No. 12622921). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12622921

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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