The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 12, 2026
Filed:
Apr. 23, 2020
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Ron C. Kelly, Westlake Village, CA (US);
Michael T. Kennedy, Newbury Park, CA (US);
Stevedat K. La, Moorpark, CA (US);
Assignee:
AMGEN INC., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/553 (2006.01); A61K 45/06 (2006.01); A61K 47/02 (2006.01); A61K 47/18 (2017.01); A61K 47/69 (2017.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/553 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); A61K 47/183 (2013.01); A61K 47/6951 (2017.08); A61P 35/00 (2018.01); A61P 35/02 (2018.01);
Abstract
The present disclosure is drawn to pharmaceutical formulations, aqueous solutions, and methods of treating cancer using the disclosed pharmaceutical formulations and aqueous solutions. The formulations and solutions comprise compounds of Formula I and may further comprise a cyclodextrin compound, such as hydroxypropyl-β-cyclodextrin and a buffer, such as glycine. The methods of treating cancer include the treatment of hematological malignances such as acute myelogenous leukemia, multiple myeloma, and non-Hodgkin's lymphoma.