The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2026
Filed:
May. 03, 2021
Wisconsin Alumni Research Foundation, Madison, WI (US);
Universiteit Leiden, EZ Leiden, NL;
University of Chicago, Chicago, IL (US);
David C. Schwartz, Madison, WI (US);
Kristy Kounovsky-Shafer, Kearney, NE (US);
Juan Hernandez-Ortiz, Medellin, CO;
Theo Odijk, Leiden, NL;
Juan Depablo, Chicago, IL (US);
Kyubong Jo, Seoul, KR;
Wisconsin Alumni Research Foundation, Madison, WI (US);
Universiteit Leiden, EZ Leiden, NL;
University of Chicago, Chicago, IL (US);
Abstract
Systems and methods for presenting nucleic acid molecules for analysis are provided. The nucleic acid molecules have a central portion that is contained within a nanoslit. The nanoslit contains an ionic buffer. The nucleic acid molecule has a contour length that is greater than a nanoslit length of the nanoslit. An ionic strength of the ionic buffer and electrostatic or hydrodynamic properties of the nanoslit and the nucleic acid molecule combining to provide a summed Debye length that is greater than or equal to the smallest physical dimension of the nanoslit.