The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2026

Filed:

Mar. 24, 2022
Applicant:

Guangdong Ocean University, Zhanjiang City, CN;

Inventors:

Saiyi Zhong, Zhanjiang City, CN;

Gege Zuo, Zhanjiang City, CN;

Jing Chen, Zhanjiang City, CN;

Jianping Chen, Zhanjiang City, CN;

Rui Li, Zhanjiang City, CN;

Bingbing Song, Zhanjiang City, CN;

Kangjian Chen, Zhanjiang City, CN;

Xiaofei Liu, Zhanjiang City, CN;

Xuejing Jia, Zhanjiang City, CN;

Assignee:

GUANGDONG OCEAN UNIVERSITY, Zhanjiang City, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/04 (2006.01); C12N 9/54 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
C12P 19/04 (2013.01); C12N 9/54 (2013.01); C12N 9/6408 (2013.01); C12Y 304/21062 (2013.01);
Abstract

This present disclosure provides a method for preparing chondroitin sulfate from tilapia skull, including enzymatic hydrolyzing tilapia skull powder by Savinase 16L to obtain Savinase 16L enzymatic hydrolysate, re-enzymatic hydrolyzing the Savinase 16L enzymatic hydrolysate by 2709 alkaline protease, then separating and purificating the solution by ethanol and cetylpyridine chloride to obtain the chondroitin sulfate. The present disclosure adopts a compound enzymatic hydrolyzing method by Savinase 16L and 2709 alkaline protease to effectively achieve the efficient extraction of chondroitin sulfate of tilapia skull powder, and further achieve the purification of chondroitin sulfate by ethanol and cetylpyridine chloride, so that tilapia by-products can be utilized with high value.


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Zhong, Saiyi. (2026). Method for increasing the extraction rate of chondroitin sulfate prepared from tilapia skull (U.S. Patent No. 12618090). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12618090

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