The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2026
Filed:
Jan. 25, 2021
Applicant:
Alteogen Inc., Daejeon, KR;
Inventors:
Soon Jae Park, Daejeon, KR;
Hye-Shin Chung, Daejeon, KR;
Seung Joo Lee, Daejeon, KR;
Kyuwan Kim, Daejeon, KR;
Hyung-Nam Song, Daejeon, KR;
Sun-Ah You, Daejeon, KR;
Chang Woo Lee, Daegu, KR;
Assignee:
ALTEOGEN Inc., Daejeon, KR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/26 (2006.01); A61K 45/06 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2474 (2013.01); A61K 45/06 (2013.01); C12N 15/63 (2013.01); C12N 2320/30 (2013.01);
Abstract
Disclosed are novel PH20 variants or fragments thereof with improved thermal stability and enzymatic activity of human hyaluronidase, which is an enzyme that hydrolyzes hyaluronic acid, and more particularly novel PH20 variants or fragments thereof including one or more amino acid residue substitutions in the variant having the amino acid sequence of SEQ ID NO: 3, wherein one or more amino acid residues at the N-terminus and/or the C-terminus are optionally further deleted.