The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2026
Filed:
Feb. 02, 2018
Amgen Research (Muncih) Gmbh, Munich, DE;
Amgen Inc., Thousand Oaks, CA (US);
Arnold Mcauley, Moorpark, CA (US);
Pavan Ghattyvenkatakrishna, Newbury Park, CA (US);
Jeff Abel, Simi Valley, CA (US);
Joon Huh, Culver City, CA (US);
Cornelius Pompe, Munich, DE;
Sekhar Kanapuram, Thousand Oaks, CA (US);
Michael Treuheit, Newbury Park, CA (US);
Bharadwaj Jagannathan, Thousand Oaks, CA (US);
Amgen Research (Munich), GmbH, Munich, DE;
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present disclosure provides a low pH pharmaceutical composition comprising (a) an antibody constructs comprising a first domain binding to a target cell surface antigen, a second domain binding to a second antigen and preferably a third domain, which is a specific Fc modality, (b) at least one buffer agent, (c) at least one saccharide, and (d) at least one surfactant; and wherein the pH of the pharmaceutical composition is in the range of 3.5 to 6.