The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2026

Filed:

Apr. 01, 2022
Applicant:

University of Cincinnati, Cincinnati, OH (US);

Inventors:

Edward Merino, Cincinnati, OH (US);

Steve Davidson, Cincinnati, OH (US);

Priyangika Senevirathne, Cincinnati, OH (US);

Assignee:

University of Cincinnati, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); A61K 31/69 (2006.01); A61P 25/36 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); A61K 31/69 (2013.01); A61P 25/36 (2018.01);
Abstract

Naloxone variants that are both long lasting and responsive are disclosed. One version of the compound has a boron ester functional group and the antagonist compound is capable of a sustained release of antagonist based on reaction with hydrogen peroxide. In addition, a method of treating opioid overdose is disclosed. The method involves administering a therapeutically effective amount of the formulation described above to a patient in need thereof. Administration occurs either intranasally, sublingually or intranasally and sublingually, wherein if administration occurs intranasally and sublingually administration occurs simultaneously, sequentially or concomitantly.


Find Patent Forward Citations

Merino, Edward. (2026). Long lasting opioid reversal using hydrogen peroxide-induced release in blood (U.S. Patent No. 12617807). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12617807

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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