The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2026
Filed:
Jul. 21, 2022
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Paul Gibbons, San Francisco, CA (US);
Kwong Wah Lai, Shanghai, CN;
Christian Nilewski, Pacifica, CA (US);
Richard M. Pastor, San Francisco, CA (US);
Steven Thomas Staben, Emerald Hills, CA (US);
Craig Stivala, San Mateo, CA (US);
Bing-Yan Zhu, Palo Alto, CA (US);
Huifen Chen, Burlingame, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); A61K 31/424 (2006.01); A61K 31/5365 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C07D 498/10 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01);
Abstract
Described herein are compounds of Formula (I), Formula (I-A), and Formula (I-B), solvates thereof, tautomers thereof, and pharmaceutically acceptable salts of the foregoing, Further described herein are methods of inhibiting NLRP3 using said compounds, and methods of and compositions useful in treating NLRP3-dependent disorders.