The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 05, 2026

Filed:

Feb. 05, 2021
Applicant:

The Rockefeller University, New York, NY (US);

Inventors:

Ksenia Gnedeva, Malibu, CA (US);

A. James Hudspeth, New York, NY (US);

Nathaniel Kastan, New York, NY (US);

Rui Liang, East Brunswick, NJ (US);

Peter T. Meinke, Scotch Plains, NJ (US);

David John Huggins, New York, NY (US);

Nigel John Liverton, San Antonio, TX (US);

Leigh Ashley Baxt, New York, NY (US);

John David Ginn, New York, NY (US);

Robert Walter Myers, Cresskill, NJ (US);

Assignee:

The Rockefeller University, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract

N-(3-Substituted thiazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamides and N-(3-substituted oxazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamides are disclosed. The compounds activate Yap and inhibit Lats kinases. They are therefore useful for treating hearing loss.


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