The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2026
Filed:
Mar. 30, 2021
The Wistar Institute, Philadelphia, PA (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Maureen E. Murphy, Philadelphia, PA (US);
Joseph Salvino, Philadelphia, PA (US);
Donna L. George, Philadelphia, PA (US);
Julia Leu, Philadelphia, PA (US);
The Wistar Institute, Philadelphia, PA (US);
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Abstract
The disclosure provides in one aspect compounds, and compositions comprising such compounds, that can be used to treat, ameliorate, and/or prevent cancer, especially colorectal cancer (CRC). In certain embodiments, the compounds of the disclosure inhibit HSP70. In other embodiments, the compounds of the disclosure promote or increase immune cell recruitment to a cancer. In yet other embodiments, the compounds of the disclosure promote and/or increase immune cell infiltration in a cancer.