The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 05, 2026
Filed:
May. 20, 2022
University of Virginia Patent Foundation, Charlottesville, VA (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Kenneth Craig Kent, Charlottesville, VA (US);
Lian-Wang Guo, Madison, WI (US);
Takuro Shirasu, Charlottesville, VA (US);
Bowen Wang, Charlottesville, VA (US);
Shaoqin Gong, Middleton, WI (US);
Nisakorn Yodsanit, Madison, WI (US);
University of Virginia Patent Foundation, Charlottesville, VA (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
In one aspect, the disclosure relates to unimolecular micelles having N-hydroxysuccinimide ester (NHS), sulfo-NHS terminal groups, or other adhesive terminal groups, compositions including the same, methods of making the same, and methods of treating intimal hyperplasia in a subject using the same. In some aspects, the unimolecular micelles can further include fluorescent labels or drugs for treating intimal hyperplasia. In one aspect, the unimolecular micelles and compositions comprising the same are biocompatible, non-toxic, and non-inflammatory. In another aspect, the unimolecular micelles and compositions are substantially free from hydrogel, or are completely free from hydrogel. In still another aspect, the disclosed compositions and methods can be easily and quickly deployed in the operating room. Also disclosed is a method of applying the unimolecular micelles and compositions via direct penbrush painting.