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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12613235 B1

PDFFull Text
Date of Patent:
Apr. 28, 2026

Filed:

Feb. 16, 2024

Method and kit for characterizing dopaminergic progenitor cells obtained by differentiating pluripotent stem cells

Applicant:

Miltenyi Biotec B.v. & Co. KG, Bergisch Gladbach, DE;

Inventors:

Melanie Jungblut, Bergisch Gladbach, DE;

Andreas Bosio, Cologne, DE;

Sebastian Knobel, Cologne, DE;

Agnete Kirkeby, Hellerup, DK;

Malin Parmar, Lund, SE;

Assignee:

MILTENYI BIOTEC B.V. & CO. KG, Bergisch Gladbach, DE;

Attorney:

Kilpatrick Townsend & Stockton LI.F

Primary Examiner:

David W Berke-Schlessel

Assistant Examiner:

Trent R Clarke

Int. Cl.
CPC ...
G01N 33/58 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5005 (2013.01); G01N 33/58 (2013.01);
Abstract

This disclosure provides a method and kit for analyzing compositions of human floorplate mesencephalic dopaminergic (mesDA) progenitor cells that are obtained, for example, by differentiating embryonic stem cells. The mesDA progenitors are characterized using the positive markers FOXA2. OTX2, and optionally NKX2. 1. in combination with the negative markers OCT3/4, and optionally PAX6, and SOXI. Cells with an appropriate protein expression profile have therapeutic potential for restoring the function of dopaminergic neurons in conditions such as Parkinson's Disease.

Find Patent Forward Citations

Jungblut, Melanie. (2026). Method and kit for characterizing dopaminergic progenitor cells obtained by differentiating pluripotent stem cells (U.S. Patent No. 12613235). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12613235

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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