The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2026

Filed:

Mar. 15, 2024
Applicant:

Pivot Bio, Inc., Minnetonka, MN (US);

Inventors:

Sarah Bloch, Berkeley, CA (US);

Karsten Temme, Berkeley, CA (US);

Alvin Tamsir, Berkeley, CA (US);

Douglas Higgins, Berkeley, CA (US);

Austin Davis-Richardson, Berkeley, CA (US);

Rosemary Clark, Berkeley, CA (US);

Shayin Gottlieb, Berkeley, CA (US);

Assignee:

Pivot Bio, Inc., Minnetonka, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 15/74 (2006.01); C12Q 1/6869 (2018.01); C12Q 1/689 (2018.01);
U.S. Cl.
CPC ...
C12N 15/74 (2013.01); C12N 1/20 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/689 (2013.01); C12Q 2600/156 (2013.01);
Abstract

The present disclosure provides guided microbial remodeling (GMR) methods for the rational improvement of plant-associated microbes to perform plant-beneficial functions. The GMR methods described herein allow for non-intergeneric genetic optimization of key regulatory networks within the microbes, which improve plant-beneficial functions over wild-type microbes but don't have the risks associated with transgenic approaches (e.g., unpredictable gene function, public and regulatory concerns, etc.). The present disclosure also provides remodeled microbes and compositions thereof. The utilization of remodeled microbes and compositions thereof will enable farmers to realize more productive and predictable crop yields without the nutrient degradation, leaching, or toxic runoff associated with traditional synthetically derived fertilizers.


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