The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2026

Filed:

Apr. 20, 2023
Applicant:

Sciperio, Inc, Orlando, FL (US);

Inventors:

Trevor Sasserath, Orlando, FL (US);

Janice M. Moser, Oviedo, FL (US);

Casey W. Perkowski, Winter Park, FL (US);

Pierce J. Busse, Pensacola, FL (US);

Kelly Haupfear, Titusville, FL (US);

Kenneth H. Church, Orlando, FL (US);

Assignee:

Sciperio, Inc, Orlando, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 1/06 (2006.01); C12M 1/34 (2006.01); C12M 3/06 (2006.01);
U.S. Cl.
CPC ...
C12M 39/00 (2013.01); C12M 1/06 (2013.01); C12M 23/16 (2013.01); C12M 29/18 (2013.01); C12M 41/16 (2013.01);
Abstract

A method includes directing fluid flow from a bioreactor to an external path of a re-circulation loop, separating cells from the medium and returning the cells to the bioreactor thereby leaving spent medium, depleting the spent medium of biological waste products, replenishing the spent medium with beneficial growth factors to thereby provide replenished medium, and directing the replenished medium back to the bioreactor to thereby complete the re-circulation loop such that recycling of the medium occurs. The replenishing of the spent medium with beneficial growth factors may occur within a medium collection reservoir. The method may further include monitoring the spent medium within the medium collection reservoir including temperature of the spent medium within the medium collection reservoir and pH of the spent medium within the medium collection reservoir.


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