The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2026

Filed:

Oct. 12, 2021
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Amit Patel, Baltimore, MD (US);

Donald Zack, Baltimore, MD (US);

Derek Welsbie, Rancho Sante Fe, CA (US);

Cynthia Berlinicke, Baltimore, MD (US);

Brendan N. Lilley, Baltimore, MD (US);

Byung-Jin Kim, Baltimore, MD (US);

Hartmut Schirok, Langenfeld, DE;

William Schubert, Wuppertal, DE;

Michael Koch, Berlin, DE;

Lionel Nicolas, Berlin, DE;

Carsten Terjung, Berlin, DE;

Mario Lobell, Berlin, DE;

Simon Holton, Berlin, DE;

Natalia Jungmann, Berlin, DE;

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 27/02 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 27/02 (2018.01);
Abstract

Provided herein are 4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)thiophene-2-carboxamide and 4-([1,2,4]triazolo[1,5-a]pyridin-7-yl)thiophene-2-carboxamide derivatives. Such compounds are useful, for example, for the treatment and/or prevention of neurodegenerative diseases or disorders such as ophthalmological neurodegenerative disorders. This disclosure also features compositions containing the same as well as methods of using and making the same.


Find Patent Forward Citations

Loading…