The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2026

Filed:

Jun. 05, 2020
Applicant:

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Inventors:

Seung-Schik Yoo, Wellesley Hills, MA (US);

Alexander Rotenberg, Brookline, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2020.01); A61N 7/00 (2006.01); A61N 7/02 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0028 (2013.01); A61N 7/02 (2013.01); A61N 2007/0021 (2013.01);
Abstract

An ultrasound system for use in unbinding an active agent from a plasma protein in a target site in a subject includes a transducer configured to generate acoustic pressure waves and a controller coupled to the transducer. The controller is programmed to control the transducer to produce a plurality of pulsed acoustic pressure waves in the target site of the patient. The plurality of pulsed acoustic pressure waves disrupt a plasma protein binding between the active agent and the plasma protein within the target site. The disruption of the plasma protein binding causes an increase in an amount of unbound active agent in the target site.


Find Patent Forward Citations

Quick Actions:

Yoo, Seung-Schik. (2026). System and method for unbinding of plasma protein-bound active agents using an ultrasound system (U.S. Patent No. 12611459). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12611459

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…