The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 28, 2026

Filed:

Nov. 06, 2020
Applicants:

Givaudan SA, Vernier, CH;

Avignon Université, Avignon, FR;

L'université DE Montpellier, Montpellier, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

L'institut National DE LA Sante ET DE LA Recherche Medicale, Paris, FR;

Inventors:

Doria Boulghobra, Avignon, FR;

Michael Laguerre, Le Pontet, FR;

Mathieu Tenon, Malemort du Comtat, FR;

Jérémy Fauconnier, Montpellier, FR;

Simona Birtic, Cavaillon, FR;

Pascale Elizabeth Renée Fança-Berthon, Le Thor, FR;

Cyril Reboul, Avignon, FR;

Olivier Cazorla, Montpellier, FR;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/216 (2006.01); A23L 33/105 (2016.01); A61K 36/31 (2006.01); A61P 21/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/216 (2013.01); A23L 33/105 (2016.08); A61K 36/31 (2013.01); A61P 21/06 (2018.01);
Abstract

The present invention relates to compounds having a lipid affinity of less than 15% by weight of the compound (such as a log P of −0.75 or less) for use in targeting mitochondria to reduce, inhibit or prevent the formation of mitochondrial reactive oxygen species and for use in treating or preventing a pathological condition associated with increased levels of mitochondrial reactive oxygen species, and for non-therapeutic uses, such as enhancing sports performance and reducing, inhibiting or preventing the formation of mitochondrial reactive oxygen species during exercise, resulting in maintenance of muscle strength and/or a reduction in muscle fatigue, and associated methods. The present invention also relates to extracts and compositions comprising compounds having a lipid affinity of less than 15% (such as a log P of −0.75 or less) for the same uses.


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