Method and system for calibrating a sensor during real-time operational use

Abstract

A method for calibrating a sensor during operation includes determining several raw measured values to determine several analyte concentrations of the medium, saving the raw measured values in the sensor memory, analyzing the stored raw measured values using a statistical method, selecting a first reference value from the stored raw measured values based on the analysis, assuming or setting a first expected concentration for the first reference value, converting the first reference value into a first analyte concentration using a built-in conversion function, comparing the first expected concentration with the first analyte concentration, and correcting the built-in conversion function based on the comparison.