The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 21, 2026
Filed:
Jun. 17, 2020
Applicants:
The Broad Institute, Inc., Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Feng Zhang, Cambridge, MA (US);
Jonathan Leo Schmid-Burgk, Cambridge, MA (US);
Assignees:
The Board Institute, Inc., Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07K 14/47 (2006.01); C12N 9/12 (2006.01); C12N 15/00 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1037 (2013.01); C07K 14/4726 (2013.01); C12N 9/1276 (2013.01); C12N 15/00 (2013.01); C12N 15/1024 (2013.01); C12N 15/1027 (2013.01); C12N 15/1031 (2013.01); C12Y 207/07049 (2013.01); C07K 2319/70 (2013.01); C07K 2319/80 (2013.01); C07K 2319/85 (2013.01);
Abstract
A diversity-generating system comprising: a polynucleotide comprising: a variable region within a sequence encoding a protein or polypeptide, wherein the system is configured to generate a library of diversified molecules with an efficiency of 80% as measured by number of the diversified molecules in total number of molecules. The system may further comprise a template region; and a reverse transcriptase or functional domain thereof.