The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2026

Filed:

May. 28, 2020
Applicant:

Chiesi Farmaceutici S.p.a., Parma, IT;

Inventors:

Paolo Bruno, Parma, IT;

Matteo Biagetti, Parma, IT;

Claudio Fiorelli, Parma, IT;

Charles Baker-Glenn, Parma, IT;

Hervè Van De Poel, Parma, IT;

Stephen David Penrose, Parma, IT;

Roberta Lanaro, Parma, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to compounds of formula I inhibiting P2X purinoceptor 3 (hereinafter P2Xinhibitors); particularly the invention relates to compounds that are pyridopyrimidines derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of many disorders associated with P2Xreceptors mechanisms, such as respiratory diseases including cough, asthma, idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD).


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