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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12606517 B1

PDFFull Text
Date of Patent:
Apr. 21, 2026

Filed:

Jun. 29, 2021

Ibuprofen ester derivative and emulsion preparation thereof

Applicant:

Nanjing Heron Pharmaceutical Science and Technology Co., Ltd., Jiangning District Nanjing, CN;

Inventors:

Hai Ye, Jiangning District Nanjing, CN;

Wenliang Zhou, Jiangning District Nanjing, CN;

Jialin Wang, Jiangning District Nanjing, CN;

Ying Xu, Jiangning District Nanjing, CN;

Tao Min, Jiangning District Nanjing, CN;

Tian Lv, Jiangning District Nanjing, CN;

Xingran Chen, Jiangning District Nanjing, CN;

Assignee:

NANJING HERON PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO., LTD., Nanjing, CN;

Attorney:

Kilpatrick Townsend & Stockton LLP

Primary Examiner:

Layla Soroush

Int. Cl.
CPC ...
A01N 37/00 (2006.01); A01N 25/00 (2006.01); A01N 37/12 (2006.01); A01N 37/44 (2006.01); A61K 9/107 (2006.01); A61K 31/215 (2006.01); A61K 31/24 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/24 (2006.01); A61K 47/44 (2017.01); C07C 68/06 (2020.01); C07C 69/96 (2006.01);
U.S. Cl.
CPC ...
C07C 69/96 (2013.01); A61K 9/107 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/24 (2013.01); A61K 47/44 (2013.01); C07C 68/06 (2013.01);
Abstract

The application related to an ibuprofen ester derivative and an emulsion preparation thereof. A carboxyl group of racemic ibuprofen or S-ibuprofen is derivatized so that Compound N9 and a dextrorotatory enantiomer N9(S) thereof are obtained and further prepared into an emulsion preparation, which overcomes the problems of safety and compliance of patients existing in clinical application of existing ibuprofen/dexibuprofen injections and achieves the purposes of reducing vascular irritation, increasing clinical use approaches, and improving the stability of preparations in clinical applications.

Find Patent Forward Citations

Ye, Hai. (2026). Ibuprofen ester derivative and emulsion preparation thereof (U.S. Patent No. 12606517). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12606517

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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