The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 2026

Filed:

Oct. 11, 2022
Applicant:

Terumo Bct, Inc., Lakewood, CO (US);

Inventors:

Dennis J. Hlavinka, Arvada, CO (US);

Thomas J. Felt, Boulder, CO (US);

Assignee:

Terumo BCT, Inc., Lakewood, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/34 (2006.01); G01N 21/03 (2006.01); G01N 21/17 (2006.01); G01N 21/41 (2006.01); G01N 21/85 (2006.01);
U.S. Cl.
CPC ...
A61M 1/3403 (2014.02); A61M 1/3496 (2013.01); G01N 21/0303 (2013.01); G01N 21/4133 (2013.01); G01N 21/85 (2013.01); A61M 2205/3313 (2013.01); A61M 2205/70 (2013.01); A61M 2230/20 (2013.01); G01N 2021/177 (2013.01);
Abstract

A method and system is provided that measures plasma protein levels of whole blood while a plasma donor is connected to an apheresis machine. A refractometer associated with the apheresis machine is capable of receiving a portion of a disposable tubing set including an integrated cuvette and prism. The integrated cuvette of the disposable tubing set can be inserted into a receiving space of the refractometer associated with the apheresis machine such that the light source and the sensor are oriented relative to the prism and a sensing surface of the integrated cuvette in a precise alignment. Calibration of the refractometer is made using anticoagulant pumped through the disposable tubing set including the integrated cuvette and prism. Based on a light intensity associated with this calibration, whole blood is then measured to determine plasma protein levels and donor eligibility.


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