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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12605471 B1

PDFFull Text
Date of Patent:
Apr. 21, 2026

Filed:

Jun. 02, 2023

Cromolyn derivatives and related methods of imaging and treatment

Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventor:

David R. Elmaleh, Newton, MA (US);

Assignee:

The General Hospital Corporation, Boston, MA (US);

Attorneys:

Foley Hoag LLP

Janine S. Ladislaw

Tatiana P. Headrick

Primary Examiner:

Jared Barsky

Int. Cl.
CPC ...
A61K 31/352 (2006.01); A61K 9/00 (2006.01); A61K 31/192 (2006.01); A61K 31/353 (2006.01); A61K 51/04 (2006.01); C07D 311/24 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0421 (2013.01); A61K 9/0075 (2013.01); A61K 31/192 (2013.01); A61K 31/352 (2013.01); A61K 31/353 (2013.01); C07D 311/24 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 9/0073 (2013.01); A61K 9/4808 (2013.01);
Abstract

Novel cromolyn analogs useful as imaging agents for detecting atherosclerotic plaques and for treating atherosclerosis and Alzheimer's Disease, and methods of making the cromolyn analogs, are disclosed. The cromolyn analogs have the general formula: wherein X is OH, C-Calkoxyl; Y and Z are independently selected from a C-Calkyl, C-Calkoxyl, halogen, un-substituted or C1-C6 substituted amine,F,F, or H; and n is 1, 2 , or 3; and wherein for structure (I), if n are both 1 and Y and Z are both H and X is OH.

Find Patent Forward Citations

Elmaleh, David. (2026). Cromolyn derivatives and related methods of imaging and treatment (U.S. Patent No. 12605471). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12605471

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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