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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12605358 B1

PDFFull Text
Date of Patent:
Apr. 21, 2026

Filed:

Feb. 16, 2022

Composition for preventing or treating nervous system diseases comprising compound that inhibits mtor signaling pathway as active ingredient

Applicant:

Aliad Biopharma, Yongin-si, KR;

Inventors:

Yunhee Kim, Seoul, KR;

Hyockman Kwon, Seoul, KR;

Young Taek Han, Cheonan-si, KR;

Assignee:

ALIAD BIOPHARMA, Yongin-si, KR;

Attorney:

Sughrue Mion, PLLC

Primary Examiner:

Bethany P Barham

Int. Cl.
CPC ...
A61K 31/357 (2006.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 47/02 (2006.01); A61K 47/12 (2006.01); A61K 47/14 (2017.01); A61K 47/26 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/357 (2013.01); A61K 9/0019 (2013.01); A61K 9/0043 (2013.01); A61K 9/145 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2059 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/14 (2013.01); A61K 47/26 (2013.01); A61P 25/28 (2018.01);
Abstract

The present invention relates to a novel compound that inhibits the mTOR signaling pathway, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient. The compound of the present invention was found to inhibit mTORC1 and mTORC2 activities, activate autophagy, and alleviate a series of disease symptoms associated with Alzheimer's-type dementia in dementia model animals, and thus can be effectively used as a pharmaceutical composition capable of preventing or treating nervous system diseases comprising neurodegenerative diseases and mTORopathy.

Find Patent Forward Citations

Kim, Yunhee. (2026). Composition for preventing or treating nervous system diseases comprising compound that inhibits mtor signaling pathway as active ingredient (U.S. Patent No. 12605358). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12605358

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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