The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2026
Filed:
Feb. 13, 2020
Beam Therapeutics Inc., Cambridge, MA (US);
Nicole Gaudelli, Cambridge, MA (US);
Michael Packer, Cambridge, MA (US);
Ian Slaymaker, Cambridge, MA (US);
Yi Yu, Cambridge, MA (US);
Bernd Zetsche, Cambridge, MA (US);
David A. Born, Cambridge, MA (US);
Seung-Joo Lee, Cambridge, MA (US);
Jason M. Gehrke, Cambridge, MA (US);
BEAM THERAPEUTICS INC., Cambridge, MA (US);
Abstract
The present invention features genetically modified immune cells comprising novel adenosine base editors (e.g., ABE8) having enhanced anti-neoplasia activity, resistance to immune suppression, and decreased risk of eliciting a graft-versus-host reaction or host-versus-graft reaction, or a combination thereof. The present invention also features methods for producing and using these modified immune effector cells.