The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2026

Filed:

Sep. 03, 2020
Applicant:

Chengdu Cynogen Bio-pharmaceutical Technology Co., Ltd., Chengdu, CN;

Inventors:

Hang Cheng, Chengdu, CN;

Weiyan Xiong, Chengdu, CN;

Bin Yu, Chengdu, CN;

Wei Niu, Chengdu, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61P 35/00 (2018.01);
Abstract

The present disclosure provides a class of isoxazolo[5,4-H]quinazoline compounds represented by general formula (I), which can be used to treat cell proliferation disorders, and are effective cyclin-dependent kinase (CDK) inhibitors, which have a broad-spectrum and strong inhibitory activity against CDK. The present disclosure also provides a pharmaceutical composition comprising the compound, and a method of treating and/or preventing a CDK-mediated disease in a subject, including administering the compound or the composition of the present disclosure.


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