The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2026

Filed:

Aug. 05, 2021
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Marc Nathan Wein, Wellesley, MA (US);

William J. Greenlee, Teaneck, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 403/12 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 471/10 (2006.01); C07D 487/10 (2006.01); C07D 498/10 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 471/10 (2013.01); C07D 487/10 (2013.01); C07D 498/10 (2013.01); C07D 519/00 (2013.01);
Abstract

The present application provides compounds that modulate the activity of one or more salt inducible kinases (SIKs). Pharmaceutical composition and methods of treating diseases associated with abnormal expression and/or activity of one or more SIKs are also provided.


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