The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2026
Filed:
Feb. 13, 2020
Bausch + Lomb Ireland Limited, Dublin, IE;
Joseph Paul Bullock, Fort Worth, TX (US);
Chinmay Maheshwari, Mason, OH (US);
Quintus Medley, Wellesley, MA (US);
Muneto Mogi, Waltham, MA (US);
Michela Montecchi-Palmer, Fort Worth, TX (US);
Gregory Morandi, Basel, CH;
Michael Mutz, Lörrach, DE;
Kalliopi Stasi, Waltham, MA (US);
Christopher Stephen Towler, Quincy, MA (US);
Bausch + Lomb Ireland Limited, Dublin, IE;
Abstract
The present disclosure provides polymorphs and formulations of 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile (compound I). The present disclosure further provides methods for treating ocular surface pain by administering 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile (compound I). The present invention also provides methods for treating dry eye disease and ocular hyperemia by administering 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile.