The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2026

Filed:

Sep. 13, 2019
Applicant:

William Marsh Rice University, Houston, TX (US);

Inventors:

David Yu Zhang, Houston, TX (US);

Dmitriy A. Khodakov, Houston, TX (US);

Xuemeng Zhang, Houston, TX (US);

Assignee:

William Marsh Rice University, Houston, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 7/00 (2006.01); B01L 9/00 (2006.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
B01L 7/525 (2013.01); B01L 9/52 (2013.01); B01L 2200/04 (2013.01); B01L 2200/0663 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/147 (2013.01); B01L 2300/027 (2013.01); B01L 2300/1805 (2013.01); C12Q 1/686 (2013.01);
Abstract

The disclosure describes apparatus and methods for multiplexed amplification and detection of nucleic acid targets in a sample. Embodiments of the present disclosure include a mechanical system configured to provide loading, vertical positioning and clamping of a chip; a thermal control system configured to maintain distinct temperatures of the chip, and an optical fluorescence imaging system.


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