The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 14, 2026

Filed:

May. 12, 2022
Applicants:

Ferronova Pty Ltd, Adelaide, AU;

Purdue Research Foundation, West Lafayette, IN (US);

Inventors:

Benjamin Thierry, Fitzroy, AU;

Melanie Ruth Maria Nelson, Brompton, AU;

Valentina Milanova, Mawson Lakes, AU;

Nicole Dmochowska, Glandore, AU;

Thi Hanh Nguyen Pham, Yagoona, AU;

Brian Stanley Hawkett, Mona Vale, AU;

Ramesh Mukkamala, West Lafayette, IN (US);

Philip Stewart Low, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 49/18 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0093 (2013.01); A61K 49/0032 (2013.01); A61K 49/0034 (2013.01); A61K 49/0054 (2013.01); A61K 49/1854 (2013.01); A61P 35/00 (2018.01);
Abstract

Nanoparticulate material suitable for administration to a subject, the nanoparticulate material having bound to its surface: (a) copolymeric steric stabiliser that promotes dispersion of the nanoparticulate material in a liquid, wherein the copolymeric steric stabiliser comprises (i) an anchoring polymer segment having one or more binding groups that bind the copolymeric steric stabiliser to the nanoparticulate material, and (ii) a steric stabilising polymer segment that is different from the anchoring polymer segment, and (b) copolymeric mapping moiety comprising (i) an anchoring polymer segment having one or more binding groups that bind the copolymeric mapping moiety to the nanoparticulate material, (ii) one or more mapping groups comprising an agent that specifically binds to fibroblast activation protein (FAP), and (iii) a coupling polymer segment that is different to the anchoring polymer segment, wherein the coupling polymer segment couples the anchoring polymer segment to the one or more mapping groups.


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