The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 14, 2026
Filed:
Apr. 22, 2020
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventor:
Christopher James Sloey, Newbury Park, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/32 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/32 (2013.01); A61K 9/0019 (2013.01); A61K 9/19 (2013.01); A61K 38/00 (2013.01);
Abstract
Disclosed herein are pharmaceutical compositions (formulations) having reduced viscosity, using a low molecular weight polyvinylpyrrolidone (povidone) in the case of high therapeutic protein concentration (≥70 mg/ml) formulations. The addition of arginine, such as arginine monohydrochloride or N-acetyl arginine, can further reduce viscosity. Appropriate therapeutic proteins include antibodies, such as monoclonal antibodies, and derivatives, fragments, and analogues thereof.
Sloey, Christopher. (2026). Use of low molecular weight polyvinylpyrrolidone (pvp) to reduce viscosity of high concentration protein formulations (U.S. Patent No. 12599669). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12599669
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile