The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2026
Filed:
Mar. 04, 2025
Applied Cells Inc., Santa Clara, CA (US);
Yuchen Zhou, San Jose, CA (US);
Silin Sa, San Jose, CA (US);
Liping Yu, San Jose, CA (US);
Fengxiang Pang, Qinhuangdao, CN;
Jinlong Fan, Qinhuangdao, CN;
Jimeng Zhu, Qinhuangdao, CN;
Huiyu Wang, Shanghai, CN;
Applied Cells Inc., Santa Clara, CA (US);
Abstract
A method for producing a population of T cells that express a chimeric antigen receptor (CAR) comprising the steps of providing a fluid sample including a population of T cells; labeling the population of T cells with magnetic beads; extracting the population of T cells from the fluid sample by flowing the fluid sample through a first conduit that passes through a first magnetic separator device; transducing the population of T cells to express a chimeric antigen receptor (CAR) by contacting the population of T cells with a population of lentivirus in a solution contained in an incubation container; and harvesting the population of T cells by flowing the solution through a second conduit that passes through a second magnetic separator device, wherein the first conduit, the incubation container, and the second conduit are fluidically connected by a network of fluidic lines.