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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12595299 B1

PDFFull Text
Date of Patent:
Apr. 07, 2026

Filed:

Oct. 05, 2021

Fc variants

Applicant:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

Inventors:

Tomoyuki Igawa, Shizuoka, JP;

Atsuhiko Maeda, Shizuoka, JP;

Kenta Haraya, Shizuoka, JP;

Tatsuhiko Tachibana, Shizuoka, JP;

Yuki Iwayanagi, Shizuoka, JP;

Assignee:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

Attorney:

Nixon & Vanderhye P.C.

Primary Examiner:

Prema M Mertz

Int. Cl.
CPC ...
C07K 16/24 (2006.01); A61K 39/00 (2006.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01); C07K 16/36 (2006.01); C07K 16/40 (2006.01); C07K 16/42 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); C07K 16/18 (2013.01); C07K 16/2866 (2013.01); C07K 16/36 (2013.01); C07K 16/40 (2013.01); C07K 16/4291 (2013.01); G01N 33/6854 (2013.01); A61K 2039/505 (2013.01); C07K 2317/14 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/90 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); G01N 2500/04 (2013.01);
Abstract

One nonexclusive aspect provides molecules further improved from antibodies that can bind to antigens in an ion concentration-dependent manner. An alternative nonexclusive aspect provides safe and more advantageous Fc region variants that have decreased binding to pre-existing ADA. An alternative nonexclusive aspect provides novel IL-8 antibodies that are superior as pharmaceuticals.

Find Patent Forward Citations

Igawa, Tomoyuki. (2026). Fc variants (U.S. Patent No. 12595299). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12595299

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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