The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2026

Filed:

Aug. 22, 2022
Applicant:

The George Washington University, Washington, DC (US);

Inventors:

Wenge Zhu, Germantown, MD (US);

Jing Li, Arlington, VA (US);

Ruiqin Wu, Sichuan, CN;

Yiliang Li, Hebei, CN;

Assignee:

The George Washington University, Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 233/58 (2006.01); A61K 31/16 (2006.01); A61K 31/22 (2006.01); A61K 31/27 (2006.01); C07C 235/26 (2006.01); C07C 235/74 (2006.01); C07C 235/88 (2006.01);
U.S. Cl.
CPC ...
C07C 233/58 (2013.01); A61K 31/16 (2013.01); A61K 31/22 (2013.01); A61K 31/27 (2013.01); C07C 235/26 (2013.01); C07C 235/74 (2013.01); C07C 235/88 (2013.01);
Abstract

Embodiments of the instant disclosure relate to novel methods and compositions for treating tumors resistant to platinum-based chemotherapy. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one ursolic acid derivative. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one ursolic acid derivative in combination with at least one platinum-based chemotherapeutic separately or in a combination therapy. In some embodiments, methods of treating tumors disclosed herein can include screening and/or selecting a subject suitable for treatment on the basis of SENP1 tumor expression. In other embodiments, methods of treating tumors can include administering a composition disclosed herein to a subject, the composition having a combination of at least one ursolic acid derivative and at least one platinum-based chemotherapeutic.


Find Patent Forward Citations

Quick Actions:

Zhu, Wenge. (2026). Compositions and methods for treatment of platinum-based chemotherapeutic resistant tumors (U.S. Patent No. 12595227). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12595227

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…