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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12594283 B1

PDFFull Text
Date of Patent:
Apr. 07, 2026

Filed:

Oct. 26, 2020

Mitochondria-targeted atovagone: a more potent and more effective antitumor, antimicrobial, and antimalarial drug

Applicants:

The Medical College of Wisconsin, Inc., Milwaukee, WI (US);

Aix-marseille Université, Marseilles, FR;

Inventors:

Balaraman Kalyanaraman, Milwaukee, WI (US);

Gang Cheng, Milwaukee, WI (US);

Micael Joël Hardy, Nimes, FR;

Assignees:

The Medical College of Wisconsin, Inc., Milwaukee, WI (US);

Aix-Marseille Universite, Marseilles, FR;

Attorney:

Quarles & Brady LLP

Primary Examiner:

Danah Al-Awadi

Assistant Examiner:

Chantal undefined Adlam

Int. Cl.
CPC ...
A61K 31/66 (2006.01); A61K 31/122 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07C 49/84 (2006.01); C07F 9/535 (2006.01); C07F 9/54 (2006.01);
U.S. Cl.
CPC ...
A61K 31/66 (2013.01); A61K 31/122 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07C 49/84 (2013.01); C07F 9/535 (2013.01); C07F 9/5435 (2013.01);
Abstract

The present invention provides novel mitochondria-targeted Atovaquone compounds (Mito-ATO), a mitochondria-targeted derivative of Atovaquone, and methods of using such compounds. Methods of treating cancer using mito-ATO are also provided. Methods of enhancing an anti-tumor immune response by administering mito-ATO are further provided.

Find Patent Forward Citations

Kalyanaraman, Balaraman. (2026). Mitochondria-targeted atovagone: a more potent and more effective antitumor, antimicrobial, and antimalarial drug (U.S. Patent No. 12594283). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12594283

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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