The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2026

Filed:

Nov. 05, 2021
Applicants:

SK Chemicals Co., Ltd., Seongnam-si, KR;

Standigm Inc., Seoul, KR;

Inventors:

Soo Min Lee, Seongnam-si, KR;

Jong-In Kim, Seongnam-si, KR;

Nam-Jin Gu, Seongnam-si, KR;

Jeong-Hoon Kim, Seongnam-si, KR;

Dae Hee Han, Seoul, KR;

Hee Jung Koo, Seoul, KR;

Assignees:

SK CHEMICALS CO., LTD., Seongnam-si, KR;

STANDIGM INC., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/549 (2006.01); A61P 19/02 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/549 (2013.01); A61P 19/02 (2018.01); A61P 29/00 (2018.01);
Abstract

A composition for preventing or treating a TNF-α-related disease is disclosed. The composition includes hydroflumethiazide or a pharmaceutically acceptable salt thereof as an active ingredient. The composition can effectively inhibit the expression or activity of TNF-α and exhibits an excellent treatment effect compared to methotrexate (MTX) or hydroxychloroquine (HCQ), which are rheumatoid arthritis treatment agents currently on the market, and, thus, can be effectively used for prevention or treatment of a TNF-α-related disease.


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