The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2026

Filed:

Dec. 28, 2018
Applicant:

Cell Cure Neurosciences Ltd., Jerusalem, IL;

Inventors:

Nir Netzer, Mazkeret Batya, IL;

Ofer Wiser, Jerusalem, IL;

Bat Shahaf, Jerusalem, IL;

Orit Gamburg, Modiin-Maccabim-Reut, IL;

Lior Rosenberg Belmaker, Jerusalem, IL;

Dana Hayoun Neeman, Kibbutz Nachshon, IL;

Osnat Bohana Kashtan, Jerusalem, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 1/125 (2025.01); A61K 9/00 (2006.01); A61K 35/30 (2015.01); A61K 47/02 (2006.01); A61K 47/18 (2017.01); A61K 47/20 (2006.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A01N 1/125 (2025.01); A61K 9/0048 (2013.01); A61K 35/30 (2013.01); A61K 47/02 (2013.01); A61K 47/183 (2013.01); A61K 47/20 (2013.01); A61K 47/26 (2013.01);
Abstract

Presented herein are ready to administer (RTA) retinal pigment epithelium (RPE) cell therapy compositions for the treatment of retinal degenerative diseases and injuries. A method of formulating human RPE cells for administration to a subject directly after thawing and of formulating RPE cell therapy compositions for cryopreservation and administration of the cryopreserved composition to a subject subsequent to thawing are also presented. In another aspect, the RTA composition may be formulated as a thaw and inject (TAI) composition, whereby the composition is administered by injection subsequent to thawing.


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