The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2026
Filed:
Jun. 01, 2022
The Regents of the University of California, Oakland, CA (US);
Daniel A. Low, Los Angeles, CA (US);
Dan Ruan, Los Angeles, CA (US);
Anand Santhanam, Northridge, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
A method for simultaneously registering a plurality of computed tomography (CT) scans of a region of interest of a subject including a subject's lungs for quantitative lung analysis includes receiving a plurality of CT scans of the region of interest acquired with a CT imaging system, receiving a breathing surrogate data for the subject, the breathing surrogate data comprising an amplitude for each of the plurality of CT scans and determining a deformation based on the plurality of CT scans and the breathing surrogate data using an iterative optimization process of an objective function. The objective function can include a first term based on an approximation of local changes in Hounsfield Units (HU) adjusted for breathing of the subject and a second term based on error in the conservation of mass. At least one quantitative lung parameter may be determined based on the deformation.