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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12590976 B1

PDFFull Text
Date of Patent:
Mar. 31, 2026

Filed:

Dec. 21, 2021

Detection method using both fluorescence and chemiluminescence labels

Applicant:

Access Medical Systems, Ltd., Palo Alto, CA (US);

Inventors:

Haode Chen, Shanghai, CN;

Heng Wu, Shanghai, CN;

Hong Tan, San Jose, CA (US);

Robert F. Zuk, Menlo Park, CA (US);

Assignee:

ACCESS MEDICAL SYSTEMS, LTD., Palo Alto, CA (US);

Attorneys:

PERKINS COIE LLP

Viola T. Kung

Primary Examiner:

Jennifer Wecker

Assistant Examiner:

Oyeleye Alexander Alabi

Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01D 15/08 (2006.01); B01F 33/302 (2022.01); B01F 33/3033 (2022.01); B01L 7/00 (2006.01); B01L 9/00 (2006.01); B65G 47/80 (2006.01); B82Y 20/00 (2011.01); B82Y 30/00 (2011.01); B82Y 40/00 (2011.01); C12M 1/34 (2006.01); C12M 3/06 (2006.01); C12N 1/14 (2006.01); C12N 1/20 (2006.01); C12Q 1/02 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/6844 (2018.01); C12Q 1/6848 (2018.01); C12Q 1/686 (2018.01); G01N 15/10 (2024.01); G01N 15/14 (2024.01); G01N 15/1433 (2024.01); G01N 21/29 (2006.01); G01N 21/64 (2006.01); G01N 21/65 (2006.01); G01N 21/76 (2006.01); G01N 30/02 (2006.01); G01N 30/72 (2006.01); G01N 33/543 (2006.01); G01N 33/557 (2006.01); G01N 33/574 (2006.01); G01N 33/58 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
G01N 33/74 (2013.01); G01N 21/6428 (2013.01); G01N 21/76 (2013.01); G01N 2021/6439 (2013.01); G01N 2333/585 (2013.01);
Abstract

The present invention is directed to an immunoassay method for detecting an analyte in a liquid sample; and provides accuracy and reproducibility for both high concentration and low concentration samples. The method uses both fluorescence marker and chemiluminescence marker, and reads both fluorescence signal and chemiluminescence signal. The analyte concentration is determined based on either a calibration curve for the fluorescence signal, or a calibration curve chemiluminescence signal, using a pre-established analyte concentration value.

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