The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2026

Filed:

Jul. 13, 2018
Applicant:

Institut Gustave-roussy, Villejuif, FR;

Inventors:

Charles Ferte, Bethesda, MD (US);

Elaine Johanna Limkin, Cachan, FR;

Roger Sun, Paris, FR;

Eric Deutsch, Paris, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); A61B 6/00 (2024.01); G01N 33/574 (2006.01); G06T 7/00 (2017.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01);
U.S. Cl.
CPC ...
G01N 33/5005 (2013.01); A61B 6/5217 (2013.01); G01N 33/505 (2013.01); G01N 33/574 (2013.01); G06T 7/0012 (2013.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01); G01N 2800/52 (2013.01); G01N 2800/7028 (2013.01);
Abstract

The present invention proposes a radiomics-based biomarker for detecting the presence and the density of tumor infiltrating CD8 T-cells in a solid tumor without having to use any biopsy of said tumor. The invention also proposes to use this information to assess the immune phenotype of said solid tumor. In a particular embodiment, the invention proposes to prognose the survival and/or the treatment efficiency of cancer patients treated with immunotherapy such as anti-PD-1/PD-L1 monotherapy.


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