The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2026
Filed:
Apr. 30, 2020
Applicant:
Valo Health, Inc., Lexington, MA (US);
Inventors:
Bingsong Han, Boston, MA (US);
Katherine Kayser-Bricker, Boston, MA (US);
Cuixian Liu, Boston, MA (US);
Assignee:
Valo Health, Inc., Lexington, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); C07D 277/46 (2006.01); C07D 285/06 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 277/46 (2013.01); C07D 285/06 (2013.01); C07D 417/12 (2013.01);
Abstract
The present disclosure is directed to compounds of formulas (I)-(VI), which are useful as modulators of USP36. The compounds are further useful in the inhibition of USP36 and the treatment of diseases or disorders associated with the inhibition of USP36. For instance, the disclosure is concerned with compounds and compositions for inhibition of USP36, methods of treating diseases associated with the inhibition of USP36 (e.g., certain forms of cancer), and methods of synthesis of these compounds.