The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2026

Filed:

Nov. 24, 2020
Applicants:

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;

Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang, CN;

Inventors:

Hong Liu, Shanghai, CN;

Yu Zhou, Shanghai, CN;

Haiyan Zhang, Shanghai, CN;

Yan Fu, Shanghai, CN;

Jian Li, Shanghai, CN;

Hualiang Jiang, Shanghai, CN;

Xican Tang, Shanghai, CN;

Kaixian Chen, Shanghai, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 211/38 (2006.01);
U.S. Cl.
CPC ...
C07D 211/38 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention provides a crystalline form of an acetylcholinesterase inhibitor, a preparation method therefor and application thereof. Specifically, the crystalline form is crystalline form A, crystalline form B and crystalline form C of 2-((1-(2-fluorobenzyl)-4-fluoropiperidin-4-yl) methylene)-5, 6-dimethoxy-2, 3-dihydro-1-indanone. The crystalline form of the present invention does not contain water and solvent, has high stability and low hygroscopicity, is easy to process, and is very suitable for preparing drugs for preventing and/or treating neurodegenerative diseases.


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