The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2026
Filed:
Mar. 24, 2025
Applicant:
Arvinas Operations, Inc., New Haven, CT (US);
Inventors:
Steven M. Sparks, Guilford, CT (US);
Michael Berlin, Yardley, PA (US);
Assignee:
Arvinas Operations, Inc., New Haven, CT (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/55 (2017.01); A61K 47/54 (2017.01); C07D 401/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 47/55 (2017.08); A61K 47/545 (2017.08); C07D 401/14 (2013.01); C07D 471/04 (2013.01);
Abstract
Provided herein are compounds (e.g., compounds of Formula (Ia)) that function to recruit LRRK2 protein or a mutated version thereof to an E3 ubiquitin ligase for targeted ubiquitination and subsequent proteasomal degradation.