The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2026

Filed:

Jan. 21, 2020
Applicant:

Aquilus Pharmaceuticals, Inc., Winchester, MA (US);

Inventor:

Irving Sucholeiki, Winchester, MA (US);

Assignee:

Aquilus Pharmaceuticals, Inc., Winchester, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01); A61K 45/06 (2006.01); A61P 1/00 (2006.01); A61P 25/02 (2006.01); A61P 25/28 (2006.01); C07D 409/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/404 (2013.01); A61K 45/06 (2013.01); A61P 1/00 (2018.01); A61P 25/02 (2018.01); A61P 25/28 (2018.01); C07D 409/12 (2013.01);
Abstract

The present disclosure relates generally to alkyne containing pharmaceutical agents, and in particular, to phenylethynyl-thiophene based compounds. More particularly, the present disclosure provides a class of compounds that can inhibit and/or attenuate apoptosis via caspase 3 for the treatment of various degenerative disorders. Additionally, the present disclosure relates to methods for treating specific degenerative disorders such as amyotrophic lateral sclerosis (ALS), Huntington's disease, epilepsy, spinal cord injury, complication due to diabetes, multiple sclerosis (MS), muscular dystrophy (MD), Parkinson's disease (PD), irritable bowel syndrome (IBS) and Alzheimer's disease (AD) in a patient comprising administering to the patient an effective amount of a present compound.


Find Patent Forward Citations

Sucholeiki, Irving. (2026). Compounds and methods for the treatment of degenerative disorders (U.S. Patent No. 12589090). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12589090

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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