The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2026

Filed:

Sep. 27, 2021
Applicant:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Inventors:

Sittadjody Sivanandane, Winston-Salem, NC (US);

Russel C. Sequeira, Advance, NC (US);

John D. Jackson, Clemmons, NC (US);

Anthony Atala, Winston-Salem, NC (US);

James J. Yoo, Winston-Salem, NC (US);

Assignee:

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/075 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0609 (2013.01); C12N 2501/31 (2013.01); C12N 2506/04 (2013.01);
Abstract

A method of providing a culture of oogonia stem cells comprising oogonia stem cells is provided. The method may further include culturing the oogonia stem cells with granulosa and theca cells to differentiate the oogonia stem cells into oocytes. In some embodiments, the culturing comprises including the oogonia stem cells in an in vitro follicle construct or a microcapsule comprising said granulosa and theca cells. Further described herein is a method of forming a bioengineered follicle construct capable of releasing a mature oocyte. An in vitro fertilization method using the mature oocyte is also provided.


Find Patent Forward Citations

Sivanandane, Sittadjody. (2026). Ovarian follicle cells and constructs for fertility treatment and hormone replacement therapy (U.S. Patent No. 12584104). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12584104

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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