The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2026

Filed:

Mar. 27, 2020
Applicants:

Orionis Biosciences, Inc., Waltham, MA (US);

Orionis Biosciences Bv, Zwijnaarde, BE;

Inventors:

Nikolai Kley, Waltham, MA (US);

Erik Depla, Zwijnaarde, BE;

Lennart Zabeau, Zwijnaarde, BE;

Assignees:

Orionis Biosciences, Inc., Waltham, MA (US);

Orionis Biosciences BV, Zwijnaarde, BE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 38/00 (2006.01); C07K 14/525 (2006.01); C07K 14/56 (2006.01); C07K 14/565 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); C07K 14/525 (2013.01); C07K 14/56 (2013.01); C07K 14/565 (2013.01); A61K 38/00 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/569 (2013.01); C07K 2317/92 (2013.01); C07K 2319/02 (2013.01);
Abstract

The present invention relates, in part, to agents, chimeric proteins and protein complexes that bind fibroblast activation protein (FAP) and their use as diagnostic and therapeutic agents. The present invention further relates to pharmaceutical compositions comprising the FAP binding agents, chimeric proteins and protein complexes and their use in the treatment of various diseases.


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