The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2026
Filed:
Feb. 02, 2022
Sanofi, Paris, FR;
Jidong Zhang, Paris, FR;
Yannick Benedetti, Paris, FR;
Esther Arranz, Paris, FR;
Andreas Karlsson, Paris, FR;
Marie-Priscille Brun, Paris, FR;
François Bretin, Paris, FR;
SANOFI, Paris, FR;
Abstract
The present invention relates to a compound of formula (I) wherein Rrepresents H, (C-C)alkyl-; hydroxy-(C-C)alkyl-; NH—(C-C)alkyl-; NH—(C-C)alkyl-(C-C)alkyl-; N((C-C)alkyl)-(C-C)alkyl-; (C-C)alkenyl-; (C-C)alkynyl-; phenyl(C-C)alkyl-; (C-C)cycloalkyl(C-C)alkyl-; (C-C)membered heterocycloalkyl(C-C)alkyl-; (C-C)membered heteroaryl(C-C)alkyl-; (C-C)membered heterocycloalkyl-NH—(C-C)alkyl-; and (C-C)membered heterocycloalkyl-N(C(O)—(C-C)alkyl)-(C-C)alkyl-; Rrepresents a halogen atom, a (C-C)alkyl- group or other well defined groups; and Rrepresents a deuterium atom; H, (C-C)alkyl-; (C-C)alkenyl-; (C-C)alkynyl-; (C-C)alkylthio-; —OR; —NRR; (C-C)membered heterocycloalkyl-; (C-C)membered heteroaryl-; —(C-C)membered aryl; and (C-C)cycloalkyl-. The present invention further relates to intermediates of these compounds, processes for their preparation, a medicament and a pharmaceutical composition comprising them, and their therapeutic uses, in particular as TLR7 and/or TLR8 agonists, as well as their use in a vaccine.