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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12583860 B1

PDFFull Text
Date of Patent:
Mar. 24, 2026

Filed:

Feb. 24, 2021

Processes for the preparation of multicomponent crystalline forms of active pharmaceutical ingredients using solvent vapour

Applicant:

Apotex Inc., Toronto, CA;

Inventors:

Alexander J. Stirk, Dartmouth, CA;

Fabio E. S. Souza, Mississauga, CA;

Avedis Karadeolian, Brantford, CA;

Allan W. Rey, Toronto, CA;

Fatemeh Mohammadpourmir, Canton, MI (US);

Assignee:

Apotex Inc., Toronto, CA;

Attorney:

The Webb Law Firm

Primary Examiner:

Jeffrey S Lundgren

Assistant Examiner:

Heather undefined Dahlin

Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/10 (2006.01); A61K 31/352 (2006.01); A61K 31/675 (2006.01); C07C 69/78 (2006.01); C07C 275/02 (2006.01); C07D 213/82 (2006.01); C07D 311/30 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/10 (2013.01); A61K 31/352 (2013.01); A61K 31/675 (2013.01); C07C 69/78 (2013.01); C07C 275/02 (2013.01); C07D 213/82 (2013.01); C07D 311/30 (2013.01); C07D 471/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention provides solvent-limited processes for the preparation of an existing crystalline solid form of an active pharmaceutical ingredient comprising mixing, in the presence of solvent vapour, of a solid active pharmaceutical ingredient and a pharmaceutically acceptable entity that is either a high-boiling liquid or a solid. Also provided is the use of a standard rotary apparatus, such as a rotary cone dryer, for application of the processes herein.

Find Patent Forward Citations

Stirk, Alexander. (2026). Processes for the preparation of multicomponent crystalline forms of active pharmaceutical ingredients using solvent vapour (U.S. Patent No. 12583860). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12583860

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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