The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2026
Filed:
Aug. 07, 2025
Applicants:
The Trustees of Indiana University, Bloomington, IN (US);
Kovina Therapeutics Inc., Indianapolis, IN (US);
Inventors:
Elliot J. Androphy, Indianapolis, IN (US);
Samy Meroueh, Carmel, IN (US);
Anne Rietz, Indianapolis, IN (US);
Zhijan Lu, Indianapolis, IN (US);
Assignees:
THE TRUSTEES OF INDIANA UNIVERSITY, Bloomington, IN (US);
KOVINA THERAPEUTICS INC., Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61K 31/5377 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 471/04 (2006.01); C07D 487/08 (2006.01); C07D 487/10 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 471/04 (2013.01); C07D 487/08 (2013.01); C07D 487/10 (2013.01); C07D 495/04 (2013.01);
Abstract
Compositions and methods are provided for treating HPV infections including pre-malignant and cancers. Compounds that specifically bind to the HPV E6 protein and inactivate the protein are disclosed.