The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2026

Filed:

Oct. 07, 2021
Applicant:

Redona Therapeutics, Inc., Watertown, MA (US);

Inventors:

Sven Weiler, Allschwil, CH;

Bérangère Gaucher, Allschwil, CH;

Florian Richalet, Allschwil, CH;

Stefan Reinelt, Allschwil, CH;

Thomas Radimerski, Allschwil, CH;

Andrea Aloia, Allschwil, CH;

Assignee:

Redona Therapeutics, Inc., Watertown, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); C07D 239/94 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 239/94 (2013.01); A61P 35/00 (2018.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 495/04 (2013.01);
Abstract

The invention provides compounds of formula (IA) and compounds of formula (IB) and pharmaceutically acceptable salts thereof; wherein A is selected from group (A1) and group (A2): wherein #1 is attached to the carbon atom forming the oxime moiety and wherein group (A1) is optionally substituted by one or two R10 and group (A2) is optionally substituted by one R10, and wherein R1, X, R2 and R10 are as defined in the claims, as well as methods of using the compounds to treat neoplastic diseases, in particular cancer.


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